The Crnojević printing house (Serbian: Штампарија Црнојевића, romanized: Štamparija Crnojevića) or Cetinje printing house (Serbian: Цетињска штампарија, romanized: Cetinjska štamparija), was the first printing house in Southeastern Europe; the facility operated between 1493 and 1496 in Cetinje, Zeta (modern Montenegro).

It was founded by Đurađ Crnojević, the ruler of Zeta between 1490 and 1496. The printing press was operated by Serbian Orthodox monks at the supervision of Hieromonk Makarije. The Crnojević printing press was also the first state press in the world. Five Orthodox liturgical books were printed in this printshop: Oktoih Prvoglasnik, Oktoih Petoglasnik, Psaltir, Trebnik (Molitvenik) and Cvetni Triod.

• Octoechos of the First Tone (Oktoih prvoglasnik) is the first book printed in the Cyrillic script among the South Slavs. It was finished on 4 January 1494. There are 108 copies of this book existing. It contains 270 leaves sized 29 x 21,6 cm. It is characterized by high quality and clean two-coloured printing, red and black, with nicely shaped letters. It is decorated with headpieces and initials printed from woodcuts in the spirit of the Renaissance with traces of old manuscript traditions.
• Octoechos of the Fifth Tone (Oktoih petoglasnik) represents the first illustrated South Slavic incunabulum. It is preserved in fragments, the longest one containing 37 leaves. It has six woodcut illustrations, made by an artist who managed to put rather complex compositions with many characters on a relatively small space.
• Psalter with Additions (Psaltir s posledovanjem) was printed in 1495. It is not only of liturgical and conventional but also historical and literary significance. It is decorated with three headpieces and 27 initials repeated for 221 time. There are 36 complete and partial copies preserved. The National Library of Montenegro "Đurđe Crnojević" published 650 facsimiles of the psalter in 1986.